Release date: 2017-09-07 Zika virus, which can cause serious damage to the fetal brain, may one day become an effective means of treating deadly brain cancer, glioblastoma. A new study from Washington University in St. Louis and the University of California, San Diego, said Zika virus can specifically kill stem cells in glioblastoma, which can be combined with conventional treatments to improve the survival of patients with such cancers. probability. Researchers published a paper in the Journal of Experimental Medicine on the 5th that Zika virus will bypass most tumor cells and specifically attack stem cells in glioblastoma, which is just like the current treatment of postoperative chemotherapy or radiotherapy. Means complement each other. Although the latter kills most of the tumor cells, it leaves a small amount of glioblastoma stem cells, which continue to divide and cause cancer to recur. To test whether this ability of Zika virus contributes to the treatment of brain cancer in living animals, the researchers conducted a mouse experiment. They injected the virus and placebo (saline) directly into brain tumors of cancer mice. Two weeks later, the test showed that the mice injected with the virus were significantly smaller than the mice injected with placebo; subsequent studies showed that they lived longer than the latter. The researchers said that to treat human brain cancer with Zika virus, the virus needs to be injected directly into the brain. The idea seems crazy, but the researchers believe it is safe, because the main goal of Zika virus, the neural progenitor cells, is mainly found in the fetal brain and is rare in the adult brain. Even if adults are infected with Zika virus, the symptoms will not be very serious. In addition, their research shows that Zika virus does not infect non-cancerous brain cells. To further address security issues, the researchers also studied the utility of mutant viruses. The results showed that mutant viruses that were weakened by infection were still able to grow in tumor cells but were rapidly eliminated in healthy cells. Although this mutant virus is not as effective as the original virus, it can kill glioblastoma stem cells. The researchers said they will introduce more mutations in subsequent studies to make the virus more sensitive to innate immune responses, and ultimately to the extent that the virus is unable to cause disease. Thus, the idea of ​​using Zika virus to treat glioblastoma will eventually be achieved. Editor-in-chief Other people's arsenic, my elixir. The sharp edge of the hand is used, and the right place is the scalpel. The notorious Zika virus in 2016, who was expected to be included in the drug preparation so soon. Once scientists know that it can destroy young brain cells, they think of young cells that can cope with chemotherapy and can not kill dead quail eggs. Opportunities belong to rational people, knowing that they can turn evil spirits into blessings. Source: Technology Daily X Ray Full Protection Collar,Full Protection Lead Collar,Large Area Protection Lead Collar,X Ray Lead Thyroid Neck Collar Longkou Kangxie Medical Instrument Co., Ltd , https://www.kangxiemedical.com