Domestic scholars question Han Chunyu's incident: the experimental results will not be affected by power outages

With so many laboratories around the world, the possibility of cell contamination is extremely low on different continents. When Han Chunyu explored this issue, he must give further scientific evidence. What pollution is pollution, fungal pollution, bacterial contamination, and mycoplasma pollution are different. When proposing a hypothesis, there needs to be evidence to support it.

On November 16th, an academic paper entitled "Questions about NgAgo" co-authored by 20 scholars at home and abroad was published in the journal Protein & Cell. Following the 13 Chinese scholars in October who publicly stated that they could not repeat the Han Chunyu experiment, this time, in the form of an academic paper, the NgAgo experiment could not be repeated.

Han Chunyu has repeatedly interviewed the media that Other laboratories cannot repeat the experiment because cell contamination affects the experimental results. Among the 20 scholars, Wang Yiyi from the Institute of Zoology of the Chinese Academy of Sciences and long-term research on genetic engineering technology told the author that the possibility of cell contamination in 20 domestic and foreign laboratories with genetic editing experience is extremely low.

Wang Yiyi's participation in the WeChat public account, "Drunken Heart Science," writes that these laboratories have chosen to publish these data after conducting multiple experiments to determine consistent negative experimental results. The article also called for the NgAgo technology of Han Chunyu's team not only to publish research papers, but also to apply for patents before publication. It is not a category of trade secrets, so it is obligatory to describe all the technical details in detail to ensure that other peers can Repeat the work and proceed to the next step.

Domestic scholars question Han Chunyu's incident: the experimental results will not be affected by power outages

The author talks about Wang Yiyi

"A lot of foreign countries question, domestic scholars do not speak very strange"

Author: The day before yesterday, 20 scholars including you jointly published a paper "Questions about NgAgo". Why did it come out now?

Wang Yiyi: We don’t have any special organization, including 13 of us (13 Chinese scholars from 20 scholars). The same is true. I can't do it, I will definitely ask you, if you don't do it, if you make it, you teach me how to do it, that's it. Everyone can't do it when they ask. Naturally, we think this is a problem. Basically, in July and August, everyone knows that they can't do it. We waited for a while and didn't see any repeatable results. At this time, many foreign countries questioned. We think that domestic scholars are very strange if they don't speak. What is our attitude as a peer, at least to show that we are not I won't do this experiment, not without our own opinion, so I decided to talk about it later. At the same time, because it takes time to organize and publish the data, we will first disclose it in the media (Editor: This refers to the fact that 13 Chinese scholars in real name announced in October that they cannot repeat the Han Chunyu experiment).

Author: Han Chunyu publicly stated that the only formal way of academic questioning is that the skeptics write the experimental process and data into a paper submitted to “Natural Biotechnology”. The journal receives it and transfers it to the original author, and the original author will respond. Questioning with more experimental processes and data. Do you still have the academic consideration of responding to Han Chunyu's considerations?

Wang Yiyi: Han Chunyu's statement is not comprehensive, and journal publishing is not the only way to question academically. Can communicate with peers and can be discussed in the forum. Some of our peers had an academic conference in June. During the experiment in early June, I was unable to repeat the results immediately. My first reaction was that the experimental method was incorrect or the details were not noticed. Therefore, everyone at the meeting was very open-minded to ask this new method. Han Chunyu was very good at the time, and I think the atmosphere is very good. But the advice given by Han Chunyu did not play a decisive role.

We will publish the paper because since we have said in the media that we can't repeat the experiment, we have scientific evidence to have people. Although we have tried to describe how we do experiments before, but in the end this is a scientific issue, we still have to publish scientific data. This is the only person in our field who can do it.

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