Muscovy duck parvovirus is an acute or subacute infectious disease that infringes young ducks. Mainly occurs in young ducks less than three weeks old, it is called "three weeks disease." Clinically, it is characterized by asthma, diarrhea, growth retardation, dyskinesia, and neurological symptoms. It has a high degree of infectivity and mortality and often causes serious economic losses. Dot Connected Disposable Tourniquet Type B Best Tourniquet,Tourniquet Online,Disposable Tourniquet,Tourniquet For Blood Draw GUANGDONG JIANGMEN RONGHAI MEDICAL TECHNOLOGY CO.,LTD , https://www.kimaomedical.com
As early as 1987 in China, this disease occurred in some areas where Fujian reared Muscovy ducks, and it was epidemic. Later, there were epidemic reports in Guangdong and Zhejiang. In recent years, Jiangsu, Anhui and other places have also occurred from time to time. Other countries in the world have also reported epidemics. In the autumn of 1989, the group of ducks reared in the intensive duck-rearing area of ​​western France also had an outbreak of this disease, with a mortality rate as high as 80%.
1. Pathogen and Epidemiology Muscovy ducks belong to the family of Parvovirus and Parvovirus. The virus is insensitive to ether, chloroform, trypsin, acid, and heat, but sensitive to UV-ray irradiation. Viruses cannot agglutinate human and mammalian and avian red blood cells.
Muscovy duck parvoviruses are widely found in the internal organs and intestines of diseased mussels such as the liver, spleen, kidneys, and pancreas. The treated tissue suspension was inoculated into the urine or allantoic cavity of 10 to 12-day-old susceptible goose embryos or 10 to 12-day-old susceptible Muscovy duck embryos. After 3 to 10 days, some embryos may die. The strains passed through Muscovy duck embryos or goose embryos can replicate in Muscovy duck embryo and goose embryo fibroblasts and cause cytopathic changes, but they cannot be passaged or replicated in chicken embryos and other animal cells.
Muscovy ducks that have been artificially infected with the virus can cause morbidity and death, but they do not cause disease in other birds.
The disease is mainly transmitted through the digestive tract. In the natural conditions, infection and transmission epidemic occurred only in young Muscovy ducks. Young Muscovy ducks and adult Muscovy ducks did not show obvious clinical symptoms after infection, but no other infected chicks were fed on the same land or grazing.
The disease is most susceptible to 7 to 20-day-old Muscovy ducks, the natural infection mortality rate of 30% to 80%, up to 100%, the disease is not seasonal, occurs throughout the year.
2. Clinical symptoms Young muscovy duck suffers from mental depression, cold, shrinking his head and wings, loss of appetite or waste, asthma, frequent mouth breathing, nasal fluids in the liquid, diarrhea, weakness, weakness. Muscovy ducklings were obviously thin, and some of the young ducks had paraplegic phenomenon before their death. The course of disease was generally 2-7 days.
3. Pathological changes Clinically seen ducks died and the toes were purple, the heart was pale and soft. In some cases, the balloon was slightly turbid, with a small amount of cellulose oozing, mild liver enlargement, gallbladder filling, various degrees of congestion and hemorrhage of the intestinal mucosa, catarrhal inflammation, severe intestinal mucosal shedding, and intestinal thrombosis. ". In some cases, the pancreas is slightly swollen, with local congestion, and there are a number of needle-point-sized, grayish-white lesions on the surface.
4. Prevention and control measures The disease has no special antiviral drug prevention and treatment. Application of Muscovy duck parvovirus live vaccine to vaccinate shelled healthy muscovy duck within 48 hours, each subcutaneous injection of 0.2 ml can prevent the occurrence of this disease. The specific treatment of the disease depends on passive immunity, that is, the use of high-anti-muscifer duck parvovirus serum subcutaneous injection of 0.3 to 0.5 ml of young pigeons suffering from Weifang infection, and the prevention of the disease in the young ducklings emergency prevention of infection Inoculation of 1 ml can reduce and control the occurrence and prevalence of the disease.