Fudan University has developed MERS virus antibodies June 15, 2015 Source: Bio Valley Fudan University has started research on related antibodies. Huashang Daily: The MERS virus appeared in 2012. Why haven't drugs and vaccines been developed yet? Zhong Nanshan: Because this disease is a very localized disease, the infection of MERS virus is considered to be a single-line infection. Most of the infected people are infected in the local area and go to other countries. Therefore, it has not caused too much in the past. Pay attention to it. This year, there have been more infected people in a larger area, which has caused great concern in the world. Generally, the more a disease spreads and the greater the harm, the higher the enthusiasm of the research. If the disease is still spreading, related research work will also drive faster. The emergence of a new disease will inevitably promote the advancement of human medical technology. In fact, China has made some progress in MERS antibody research, but has not conducted a phase I clinical trial. The safety is not known, and it is impossible to rush to the patient, unless the patient is in danger of life. When applied to the clinic, it is first necessary to go to the laboratory for testing, then to do animal experiments, and finally to do human testing, with a longer cycle. As far as I know, the research team of the School of Basic Medicine of Fudan University cooperated with the National Institutes of Health to jointly develop a super active human-neutral neutralizing antibody M336 against MERS coronavirus. The animal experiment is very effective and hopes to be carried out as soon as possible. Clinical Trials. The MERS virus has a high viral load in the body, and it is more effective to kill the virus by the antibody, which is much faster than developing the anti-MERS virus. Why can't humans get rid of the shadow of infectious diseases? Ecological destruction, some viruses are getting closer and closer Huashang Daily: From the SARS that broke out 12 years ago to the bird flu and MERS that have appeared in recent years, the threat of cross-species infectious diseases to human life is increasing. Why is this happening? Zhong Nanshan: I think this may be caused by changes in the ecological environment. Human beings have destroyed the ecological environment and changed the habits of the past. The living space of people is getting bigger and bigger, and the living space of animals is getting smaller and smaller. This makes some viruses that are far away from each other getting closer and closer. Huashang Daily: Technology has been making progress. Why can humans never get rid of the shadow of infectious diseases? Zhong Nanshan: Due to the large ecological environment, prevention and control is difficult. The possibility of animals infecting people still exists. Even if technology advances, infectious diseases may still exist, but the outbreak will soon be brought under control. Huashang Daily: What is the most effective means of controlling infection? Zhong Nanshan: Isolation, not letting the virus spread; and we must figure out the route of transmission and control the source of infection. For example, the intermediate host of SARS is the civet, and the wild animal market is cut off. In the second year, there were only 4 cases of sporadic cases in SARS, and then there was no more. The first case of infection occurred on May 20 in South Korea. On June 8, South Korea became the world's second largest MERS disease country after Saudi Arabia. The main reason for the rapid spread is that the Korean authorities initially paid insufficient attention to MERS, and measures such as isolation and treatment were not timely enough, leading to the spread of the epidemic. After the lessons of SARS, China has been more vigilant and gradually improved the prevention and control system of infectious diseases. The level of attention to the prevention and control of infectious diseases, monitoring and testing and other technical levels have been significantly improved, in response to the H7N9 bird flu, Ebola and other epidemics Both have made great progress and are more mature and calm. This is also related to the awareness of the national consciousness, medical staff, and administrative staff.
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Fudan University has developed MERS virus antibodies
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