Causes of cancer caused by betel nut

The statement that chewing betel nut as the suspect of oral cancer has already existed. In Taiwan, Hunan, Hainan, and Guangdong, there are high incidences of oral cancer in the betel nut high-yield areas.

60% of oral cancer may be caused by chewing betel nut

According to a survey released by the WHO's Cancer Research Center, 60% of oral cancers may originate from the chewing of betel nut, and China's Taiwan and India are listed as areas where oral cancer is caused by the delicious betel nut.

The latest data show that the number of new cases of oral cancer in Taiwan has continuously increased, nearly tripled in ten years, and the death rate has surged by more than 100%. It is the fastest-growing cancer in all cancers and currently kills more than 2,000 people every year. Eating betel nut is considered by doctors to be the most important pathogenic factor. According to data from the Taiwan "Department of Health", among the top ten cancers in Taiwan, oral cancer has grown from the top ten cancers in 1992, becoming the fastest-growing cancer, and the number of people suffering from cancer has grown by 100% within 10 years. At 29.4, the death toll was 900 in 1995 and 2,000 in 2006. This year it has exceeded 2,000 and continues to rise. The World Health Organization has ranked Taiwan and India as areas of endemic oral cancer caused by the delicious betel nut.

Betel nut contains a large amount of arecoline and alkaloids, which have cytotoxicity

Now, the most popular argument for chewing betel quid oral cancer is that the most common way to eat it is to add betel nut, coriander, and lime. Betel nut contains a large amount of arecoline (which is cytotoxic and genotoxic). The more recognized carcinogens baicalein, baicalein in the human body will inhibit the synthesis of cellular DNA, leading to lesions in the oral mucosa, betel nut plus alum is equivalent to carcinogens plus cancer promoters.

Moreover, during the betel nut chewing process, the oral mucosa reacts with the alkaloids and various nitrosamine compounds contained in the betel nut. The nitrosamine compound has been considered as a basic factor causing oral mucosal lesions. Long-term mucosal exposure to this environment can cause oral mucosal lesions that cause fibrosis and can cause oral cancer.

Do not insist on daily brushing twice the risk of cancer

"Prevention of oral cancer should start from the elimination of risk factors and precancerous lesions, abstain from bad habits, avoid dangerous irritations, and maintain due diligence on suspicious oral lesions. These are the lessons that cancer prevention must do." Some points can effectively block the invasion of oral cancer:

1. Pay attention to oral hygiene, brush your teeth correctly, prevent dental caries, clean your teeth regularly, and remove dental calculus. The survey showed that people who couldn't stick to daily brushing increased the risk of tongue cancer by 2.1 times and the risk of tumors in other parts of the mouth by 2.4 times.

2. Remove bad restorations in time and go to a regular medical facility to receive repairs. Many elderly people have lost their teeth and are easily coveted and cheap. They accept dental implants in some unqualified places because of poor technology. In patients with oral ulcers caused by poor prostheses, the risk of developing oral cancer is 2.3 times higher than normal.

3. Smoking cessation of alcohol, change chewing betel nut, love eating hot and other bad habits;

4 timely treatment of precancerous lesions, such as oral leukoplakia, lichen planus, oral submucous fibrosis, chronic actinic cheilitis;

5. The law of life, on time and rest;

6. For oral ulcers that have not healed for more than two weeks, attention should be given to them and timely treatment.

Experts also pointed out that early detection of oral cancer, the majority can be cured. “The sooner the discovery, the more timely the treatment, the better the therapeutic effect and the quality of life after surgery. For early detection of oral cancer with a diameter of less than two centimeters, most of the oral cancers can be treated with local resection to achieve a standard of cure, with little effect on normal function. "If you develop into the middle and late stage, if you need to remove the larger primary lesions, lymph node metastasis will occur at this time or if lymph node dissection is often needed, so the scope, level of trauma, and expense will be greatly increased. The 5-year survival rate is also relatively low.

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