Release date: 2016-07-20 After being treated by Mayo Clinic, Jenny (left) returned to health Jenny. Jeneen Leogrande has been afflicted with leaking complications of lung cancer for up to 3 years. In the midst of almost collapsed desperation, she took advantage of an occasional opportunity to bravely try to use stem cell therapy to repair postoperative fistulas, and ultimately succeeded in “escapeâ€. This is the world's first successful case of stem cell repair for postoperative fistula of lung cancer, and it is exciting. On Christmas Eve 2011, Jenny was in the recovery period after total lung cancer, but she began to have postoperative oozing complications. The complication was not unexpected, as she had undergone a right lung resection and had removed some of the chest wall tissue and two ribs, resulting in a larger range of trauma, which eventually led to the bronchial pleural palsy of the original right lung stump. A large amount of pus leaks into the chest through the fistula, causing serious infection and fever. Because the fistula caused air leaks, breathing gas could not enter the pulmonary circulation, and could not pass the vocal cords. Jenny once had symptoms such as difficulty breathing, difficulty in making sound, decreased blood oxygen content, and lethargy, which seriously affected the quality of life. After three years, Jenny was like a nightmare. It was because of the "rubber"-sized fistula of her body that she moved from Florida to Minnesota, where she had performed more than 30 futile surgical repairs. The doctor even performed a hole-making procedure on her right chest, and drilled a softball-sized hole to drain the pus. She also had a pedicled flap to repair the fistula, which ended in failure. The doctor also told her that treatment was hopeless and suggested that she prepare to call her family to make a final farewell before her death. However, just as she almost collapsed, she ushered in a turning point, and this turning point was twisting and moving. In the fall of 2012, her husband, Frank, stumbled upon an official magazine in the Mayo Clinic. Dr. Timothy Nelson, a medical specialist at the Mayo Clinic, was studying stem cell therapy for various diseases. He immediately turned to the expert at Mayo Clinic for help. In January 2013, three days before the appointment, Jenny broke into a diffuse infection of the chest incision, and the condition turned sharply and septic shock occurred. She was hospitalized immediately after receiving a series of routine emergency treatments. Her body and mind had been greatly tortured and nearly collapsed, so she told her husband to leave the hospital to give up treatment. At this point, her husband once again turned to Dr. Nelson for help. The response was that Dr. Nelson had nothing to do with Jenny's condition and suggested that they turn to Dr. Wigle, another thoracic surgeon at the Mayo Clinic. Dr. Wigle is preparing a paper and is actively calling for the US FDA to waive the “privileged treatment†regulation of stem cell therapy. The Jennys also responded positively by requesting FDA and Mayo to receive stem cell therapy through a joint call of friends, family members and government officials, and finally got the answer. Device for extracting stem cells from abdominal adipose tissue of a patient at the Mayo Clinic One day before Thanksgiving in 2014, Dr. Wigle took 13 drops of adipose tissue from Jenny's abdominal wall and centrifuged to obtain mesenchymal stem cells (MSC) with various cell differentiation potentials for cell culture and proliferation. The research team led by Dr. Wigle obtained about 25 million mesenchymal stem cells spread on a tanning screen. After the stem cell screen was placed in the bioreactor for 4 days, the sieve was properly trimmed and transplanted for 12 hours. After that, he successfully closed Jenny’s fistula and eventually recovered. Jenny's abdominal adipose tissue extracted stem cells multiply on a special sieve "We don't know the specific mechanism of stem cell therapy to repair fistulas," Dr. Wigle said. "Jenny is the world's first success story. Although we have seen a hope that stem cell therapy can successfully repair bronchopleural fistula, it is not clear whether It’s purely accidental, it’s really worth promoting.†Dr. Wigle is designing a clinical trial that plans to include 12 patients to verify whether Jenny’s success can be extended to other patients. We sincerely hope that Dr. Wigle will succeed and benefit more patients. Source: WuXi PharmaTech Blowing Mouth,Disposable Blowing Mouth,Filter Spirometer Mouthpiece,Disposable Spirometer Mouthpiece Hengshui Qifei Paper Products Co. LTD , https://www.hengshuiqifei.com