Recently, "Lancet" first published the use of anti-aging drug Senolytics in the treatment of 14 elderly patients with mild to moderate idiopathic pulmonary fibrosis, which is the first human body test results of these drugs in the world! Each participant took two drugs: dasatinib and quercetin, taken for 3 days a week for 3 weeks, which can significantly improve the patient's mobility, alleviate the symptoms of weakness, other physiology such as grip strength and lung function. The indicator has no impact. The clinical effectiveness of the "longevity drug" will help humans continue to prolong their life. Perhaps humans will not only live to 120 years old, but also have the quality to grow old. So, can "longevity medicine" make "long life" a reality? I will give you a detailed science episode today! How does aging happen? The aging of the human body is caused by the aging of cells. When aging cells stop dividing and accumulating, especially in the aging biological immune system, aging cells cannot be removed in time, and the number gradually exceeds that of non- senescent cells. The secreted protein damages the surrounding nuclear tissue, and the tissue appears to be “oldâ€. ", resulting in a health condition. Cellular senescence is usually caused by various internal and external stimuli such as telomere shortening, protooncogene activation, oxidative stress, and cell-thin fusion, resulting in changes in cell status. Cellular aging involves many physiological phenomena, which can be beneficial to living organisms, such as inhibiting tumorigenesis, promoting wound healing, embryo development, etc.; it can also be harmful, such as the aging of organisms and the occurrence of diseases related to inflammation and aging. Wait. However, the benefits and disadvantages of aging cells generally depend on whether the aging cells are transient or persistent, the former is beneficial, and the latter is generally harmful. How is the anti-aging drug Senolytics anti-aging? Eliminating aging cells is a strategy for anti-aging and can be achieved by genetic engineering or by taking anti-aging drugs. Dasatinib is an antihistamine that is traditionally used to treat cancer and leukemia, while quercetin quercetin is an antihistamine that is traditionally used to treat cancer and inflammation as a plant growth inhibitor. In 2015, Professor Deursen and others discovered that a series of drugs can specifically induce the death of aging cells, but not a small number of non-aging cells, so these drugs are called Senolytics, used to remove human aging cells. Because different kinds of Senolytics have different mechanisms of action and different senescent cells are removed, the combined use is often better. The currently reported strains of Senolytics include dasatinib, quercetin, navitoclax (ABT263), citrate, fisetin, A1331852 and A1155463. Many drugs are undergoing clinical research and are expected to be put into use in the future. . What are the other anti-aging methods? With the prolongation of human life expectancy, cardiovascular diseases, cancer and neurodegenerative diseases, which are followed by aging, will increasingly affect the quality of life of the elderly. Therefore, scientists have studied various means to "anti-aging". . Enhance cell autophagy in specific species and special periods by specific methods, directly remove senescent cells, intermittent fasting, promote nerve formation to reverse Alzheimer's disease, regular physical exercise, take antioxidants and herbs, stem cells Treatment, etc. What method should I use to prevent aging? Enhancing the autophagy ability of cells, using Senolytics to remove senescent cells, infusion of young people's plasma, drugs to promote nerve formation, etc. are promising in anti-aging, but most of these methods are still valid in animal experiments, but also need Clinical trials to evaluate long-term efficacy and side effects. Although Senolytics has achieved certain clinical effects, in order to reduce side effects, treatment cannot be performed frequently. Stem cell therapy has been shown to promote aging brain regeneration and restore its function, but in clinical use it is necessary to evaluate the safety and efficacy of cells from different cell sources. Intermittent fasting, regular exercise, resveratrol and turmeric for the treatment of neurodegenerative diseases are preparing for large-scale clinical trials, and may also be a non-invasive, minimally side-effect method. One day in the future, we may really be able to determine our longevity, but before that day, a healthy lifestyle and a good mental state are undoubtedly the secret of longevity! (Source: Science China     Experts in this article: Dr. Tian Jing, former Chengdu Military Region Center for Disease Control and Prevention, attending physician )
Medical Cold Patch
Throat Pain Relief Patch,Throat Pain Relief Pad,Throat Pain Relief Plaster,Antitussive Patch Shandong XiJieYiTong International Trade Co.,Ltd. , https://www.xjplaster.com
Throat Pain Relief Patch
[Name] Medical Cold Patch
[Package Dimension] 36 round pieces
The pain relief patch is composed of three layers, namely, backing lining, middle gel and protective film. It is free from pharmacological, immunological or metabolic ingredients.
[Scope of Application] For cold physiotherapy, closed soft tissue only.
[Indications]
The patches give fast acting pain relief for acute and chronic tonsillitis.
[How To Use a Patch]
Please follow the Schematic Diagram. One piece, one time.
The curing effect of each piece can last for 6-8 hours.
[Attention]
Do not apply the patch on the problematic skin, such as wounds, eczema, dermatitis,or in the eyes. People allergic to herbs and the pregnant are advised not to use the medication. If swelling or irritation occurs, please stop using and if any of these effects persist or worsen.notify your doctor or pharmacist promptly. Children using the patch must be supervised by adults.
[Storage Conditions] Store below 30c in a dry place away from heat and direct sunlight.