Japan allows research on human fertilized egg gene editing

The Japan Bioethics Special Investigation Committee announced on the 22nd that it allows Japanese institutions to "edit" the genes of human fertilized eggs in basic research, but for safety and ethical considerations, it is not allowed to apply this technology to clinical and assisted reproduction.

Japan allows research on human fertilized egg gene editing

The so-called gene editing refers to the operation of knocking out the target gene or introducing the genome, and the technology has been applied in many research fields.

The Japan Bioethics Special Investigation Committee is a professional organization under the Japanese government. The committee believes that human fertilized egg gene editing research will contribute to research on reproductive assisted medical and genetic disease prevention, and may also help to develop new therapies for diseases such as cancer, so the basic research on "editing" human fertilized egg genes is given. Recognition.

The committee pointed out that the dividing line between basic research and clinical research involving fertilized egg gene editing is whether to put genetically edited fertilized eggs into the uterus. Because of the safety and ethical issues in clinical research, the committee does not endorse such research. Even if it belongs to the basic research category, it is not that any research is licensed. For example, infant research that “designs” specific looks and abilities according to the wishes of parents is an ethical issue and will not be allowed. In addition, basic research on the editing of fertilized egg genes must also disclose implementation and maintain transparency.

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