CAS 13647-35-3 Pharmaceutical Intermediates Trilostane as Anti - Tumor Drugs

Model NO.: Trilostane
CAS: 13647-35-3
Mf: C20h27no3
Einecs: 237-133-0
Purity (HPLC): 99.0%Min.
Appearance: White Crystalline Powder
Trademark: Nanjian
Transport Package: According to Customer Requirements for Packaging
Specification: ISO 9001
Origin: China
HS Code: 3001200020
Model NO.: Trilostane
CAS: 13647-35-3
Mf: C20h27no3
Einecs: 237-133-0
Purity (HPLC): 99.0%Min.
Appearance: White Crystalline Powder
Trademark: Nanjian
Transport Package: According to Customer Requirements for Packaging
Specification: ISO 9001
Origin: China
HS Code: 3001200020
Cas 13647-35-3 Pharmaceutical Intermediates Trilostane As Anti - Tumor Drugs

Quick Detail:

1. Trilostane
2. CAS No.: 13647-35-3
3. Purity: 98.5%min
4. Other Names: 4a,5a,17b)-3,17-Dihydroxy-4,5-epox...  
5. MF: C20H27NO3  
6. EINECS No.: 237-133-0
7. Appearance: White to off-white power    
8. Type: Antineoplastic Agents  
9. Grade Standard: Medicine Grade  
10. Packing: As customers requirments
11. Usage: Anti-tumor drugs and immunosuppressants

Description:

Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
It was withdrawn from human use in the United States market in April 1994.[3][4] The drug is available in the United Kingdom for use in humans under the brand name Modrenal and is used for treatment of Cushing's disease and for breast cancer treatment
 
Applications:
Albuterol Sulfate/Ventolin powders/Proventil powders/CAS No: 51022-70-9
It is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices (e.g. Rotahaler or Autohaler). In these forms of delivery, the maximal effect of salbutamol can take place within five to 20 minutes of dosing, though some relief is immediately seen. It can also be given intravenously.
Used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients bronchospasm.
 
 Packaging & Delivery Process:
 
1.   Sufficient stock, to delivery promptly at the very day when receive the payment
2.   Sophisticated and professional logistic agent.
3.   Well-trained and disciplined packing team. Unique ways to ship 2 mgial to 20mgial at one time to       your destination. Fast and discreet shipment could be arranged for customs pass Guaranteed.
4.   Packing pictures and tacking code are provided within 12 hours after receiving the payment.              Updated tracking information will be provided every other day.
5.   After-sale service: Any questions or problems after receiving the product, please feel free to             contact us. Problems would be solved immediately.
 
Specifications(coa and hplc):
 

Test Items

Specification

Test Results

Appearance

white oralmost white,crystalline powder

Conform

Solubility

Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride.

Conform

Identification

A

The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64.

Conform

B

Infraed absorption spectrophotometry.

Conform

C

Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution.

Conform

D

An orange-red color develop in methylene chloride layer.

Conform

E

It geves reaction (a) of sulphates.

Conform

Appearance of solution

Solution S is clear and not more intensely coloured than reference solution in BY6.

Conform

Optical rotation

negative 0.10° to +0.10°determined on solution S.

+0.01°

Acidity or alkalinity

NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red.

Conform

Related substances

Impurity J ≤0.20%

Conform

Any other impurity ≤0.30%

Conform

Total impurity ≤1.0%

Conform

Boron

≤50ppm

Conform

Sulphated ash

≤0.10%

0.06%

Loss on drying

≤0.5%

0.30%

Assay(on dried basis)

98.0~101.0%

99.5%

Conclusion

The test results above BP2009

 
Competitive Advantage: 

1.Offer best quanlity and competitive price.
2.well experienced in delivering the parcels to you.
3.Full stock ensures prompt delivery.
4.Superior after-sales service.
5.Package will be reshipped if sent unseccessfully.
6.Experiential shopping .Besides raw steroid powder and liquid, we offer steroid solutions and recipes. We can 
teach you how to make steroid solutions on the site. Any visit to our lab is welcomed.
 

Keywords :

 
Treatment of cushing's syndrome
Pharmaceutical intermediates;
 

Related products:
 

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2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester

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Cas 13647-35-3 Pharmaceutical Intermediates Trilostane As Anti - Tumor Drugs

Quick Detail:

1. Trilostane
2. CAS No.: 13647-35-3
3. Purity: 98.5%min
4. Other Names: 4a,5a,17b)-3,17-Dihydroxy-4,5-epox...  
5. MF: C20H27NO3  
6. EINECS No.: 237-133-0
7. Appearance: White to off-white power    
8. Type: Antineoplastic Agents  
9. Grade Standard: Medicine Grade  
10. Packing: As customers requirments
11. Usage: Anti-tumor drugs and immunosuppressants

Description:

Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
It was withdrawn from human use in the United States market in April 1994.[3][4] The drug is available in the United Kingdom for use in humans under the brand name Modrenal and is used for treatment of Cushing's disease and for breast cancer treatment
 
Applications:
Albuterol Sulfate/Ventolin powders/Proventil powders/CAS No: 51022-70-9
It is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices (e.g. Rotahaler or Autohaler). In these forms of delivery, the maximal effect of salbutamol can take place within five to 20 minutes of dosing, though some relief is immediately seen. It can also be given intravenously.
Used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients bronchospasm.
 
 Packaging & Delivery Process:
 
1.   Sufficient stock, to delivery promptly at the very day when receive the payment
2.   Sophisticated and professional logistic agent.
3.   Well-trained and disciplined packing team. Unique ways to ship 2 mgial to 20mgial at one time to       your destination. Fast and discreet shipment could be arranged for customs pass Guaranteed.
4.   Packing pictures and tacking code are provided within 12 hours after receiving the payment.              Updated tracking information will be provided every other day.
5.   After-sale service: Any questions or problems after receiving the product, please feel free to             contact us. Problems would be solved immediately.
 
Specifications(coa and hplc):
 

Test Items

Specification

Test Results

Appearance

white oralmost white,crystalline powder

Conform

Solubility

Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride.

Conform

Identification

A

The UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64.

Conform

B

Infraed absorption spectrophotometry.

Conform

C

Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution.

Conform

D

An orange-red color develop in methylene chloride layer.

Conform

E

It geves reaction (a) of sulphates.

Conform

Appearance of solution

Solution S is clear and not more intensely coloured than reference solution in BY6.

Conform

Optical rotation

negative 0.10° to +0.10°determined on solution S.

+0.01°

Acidity or alkalinity

NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red.

Conform

Related substances

Impurity J ≤0.20%

Conform

Any other impurity ≤0.30%

Conform

Total impurity ≤1.0%

Conform

Boron

≤50ppm

Conform

Sulphated ash

≤0.10%

0.06%

Loss on drying

≤0.5%

0.30%

Assay(on dried basis)

98.0~101.0%

99.5%

Conclusion

The test results above BP2009

 
Competitive Advantage: 

1.Offer best quanlity and competitive price.
2.well experienced in delivering the parcels to you.
3.Full stock ensures prompt delivery.
4.Superior after-sales service.
5.Package will be reshipped if sent unseccessfully.
6.Experiential shopping .Besides raw steroid powder and liquid, we offer steroid solutions and recipes. We can 
teach you how to make steroid solutions on the site. Any visit to our lab is welcomed.
 

Keywords :

 
Treatment of cushing's syndrome
Pharmaceutical intermediates;
 

Related products:
 

Product name

Cas no

Chlorhexidine hydrochloride

3697-42-5

Tinidazole

19387-91-8

2,3,4-trimethoxybenzaldehyde

2103-57-3

Nystatin

1400-61-9

Vernine

118-00-3

 

50-02-2

7-amino-3-methyl-3-cephem-4-carboxylic acid

22252-43-3

O-phenylenediamine

95-54-5

5-difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1h-benzimidazole

102625-64-9

Amikacin disulfate salt

39831-55-5

(s)-2-benzothiazolyl (z)-2-(2-aminothiazole-4-yl)-2-methoxycarbonylmethoxyiminothioacetate

246035-38-1

3-methylflavone-8-carboxylic acid

3468-01-7

(2s-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid

80082-65-1

4-(difluoromethoxy)-3-(cyclopropylmethoxy)-benzaldehyde

151103-09-2

2,4-dihydroxy-6-methylpyrimidine

626-48-2

3,3-dimethyl-1-butyne

917-92-0

Pheniramine maleate

132-20-7

Beta-d-glucose pentaacetate

604-69-3

 

55268-74-1

4-(3'-methylphenyl)amino-3-pyridinesulfonamide

72811-73-5

2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester

136285-65-9

[2-chloro-1-(chloromethyl)ethoxy]methanol acetate

89281-73-2

Thymidine, 4-thio-

7236-57-9

Dl-glutamic acid

617-65-2

(r)-(+)-1-phenylethylamine

3886-69-9

1-[2-(dimethylamino)ethyl]-1h-tetrazole-5-thiol

61607-68-9

Tetrahydro-2-methyl-3-thioxo-1,2,4-triazine-5,6-dione

58909-39-0

2-[[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino]-3-nitro-benzoic acid ethyl ester

136285-67-1