The main differences between powder,premixed agent, granule are as follows:
Veterinary Soluble Powder: means a dry powder preparation made of one or more drugs by grinding and evenly mixing, with or without dressing.
Premix: refers to one or more drugs, and a suitable substrate evenly mixed to make a powder or granular preparation.
As a dosage form of feed drug additive, it is specially used for mixed feeding.
Powder powder, that is, powder, and premixed agent, the main differences of granules are as follows:
1.the production method is different
1.powder: medicine or with appropriate auxiliary materials by grinding, evenly mixed dry powder preparation.
2.Veterianary premix: powder or granular preparation made by evenly mixing the drug with an appropriate substrate.
3.granules: raw materials and appropriate excipients mixed into a certain particle size of dry granular preparation.
2.different characteristics
1. Dispersing agent: compared with other solid dosage forms, dispersing agent is easy to disperse, dissolves quickly, absorbs quickly and takes effect quickly; The preparation process is simple, the dosage is easy to control, and it is easy for infants to take.
2.Premix for animal: Premix used in the matrix including carrier, diluent, etc. The substrate should be stable, with good fluidity, and easy to mix with drugs and feed.
3. Granule: the dispersion, adhesion, agglomeration and hygroscopicity of granule are lower than that of granule; The separation of various components in granule is avoided because of the adhesive used to make granule after mixing. Convenient storage and transportation; Particles can change their function by coating.
Veterinary drug premix,Premix for animal,Veterinary premix,Poultry premix feed NANYANG CHENGPENG PHARMACEUTICAL CO.,LTD , https://www.cpbiopharmacy.com
The main points of Hericium bag cultivation techniques are:
1 Preparation of culture materials
1 78% cottonseed hull, 20% bran, 1% sucrose, and 1% plaster.
2 Corncob 78%, bran 20%, sucrose 1%, gypsum 1%. 1.3 40% cotton seed hull, 30% wood chips, 25% bran, 2% corn flour, 1% gypsum powder, 1% sucrose, 1% potassium dihydrogen phosphate.
Production can be based on the supply of raw materials and production scale to select one of the raw materials. The raw materials are required to be fresh and free of mildew. Mix the ingredients evenly after they are ready, then add water and mix well. The water content is in the range of 60% to 70%, and the P(H) value is in the range of 4.50 to 6.50 (taking into account that the culture medium will be gradually acidified during the subsequent culture, therefore, the P(H) value at this time is preferably 6.50). Then boring about 30 minutes or bagging, note that if the formula 2 is used, the corn cob needs to be crushed into the size of the soy bean, soaked in water one day in advance to make it fully soaked, and then remove the excess water before use and drain it. Mix with other ingredients.
2 bagging, sterilization, inoculation
1 After the bagging culture material is prepared, it is bagged. The plastic bag size is 35 cm x 17 cm x 0.05 cm. The polypropylene bag is used for autoclaving and the polyethylene bag can be used for normal pressure sterilization. About 450 grams of dry material is placed in each bag, and it is required to be loaded and elastic. Fill with a hard plastic collar and fill with the lid. In this case, check whether the plastic bag, collar, lid, etc. are damaged, and if necessary, replace them.
2.1 Bagging culture materials are ready to be bagged. The plastic bag size is 35cm x 17cm x 0.05cm. Polypropylene bags are used for autoclave sterilization. Polyethylene bags can be used for normal pressure sterilization. About 450 grams of dry material is placed in each bag, and it is required to be loaded and elastic. Fill with a hard plastic collar and fill with the lid. In this case, check whether the plastic bag, collar, lid, etc. are damaged, and if necessary, replace them.
2.2 Sterilization Sterilization is carried out at normal pressure and autoclave. Normal pressure sterilization is carried out at normal pressure for 12 hours and autoclaving at 1.50 kg/cm2 for 2 hours. After the end of the sterilization, the bag is taken out and checked for damage and the influent bag and then moved into the inoculation room for inoculation.
2.3 Inoculation Start the inoculation when the bag temperature is below 30°C. The inoculation was performed in a sterile inoculation chamber. In order to shorten the germination time, two inoculations are used, that is, one at the mouth of the bag and one at the bottom of the bag. Immediately after the cover is covered, the taper or special sealing membrane seals the hole.
3 Bacteria management 1 Temperature and humidity management, control of room temperature at 22-24°C by means of watering, shade, and ventilation. Humidity below 70%.
2 Lighting Management. As the Hericium mycelium growth stage does not require light, so the culture room needs to be shaded and kept dark for mycelial growth.
3 After the other management moved into the bacterium culture room for about 3 to 4 days, the hyphae had begun to eat. At this time, it was necessary to check whether there was any contamination or not and to check out the contaminated material bags. In addition, check for the presence of rats and other hazards.
4 Management of the fruiting body generation period After about 25 to 30 days of cultivation, the hyphae have already filled the bag or are about to fill the bag. At this time, the temperature of the culture room can be reduced to 20-22°C through ventilation and ventilation. And remove the shade to increase the scattered light to stimulate, after about 7 days on the material surface began to appear buds can be moved to the mushroom shed or adjust the temperature of the bacteria chamber to 18 ~ 20 °C, unplug the lid, remove Collar fruiting. At this point to maintain the relative humidity of 85% to 90%, increase the scattering of light, and pay attention to appropriate ventilation, so that after about 15 days of fruiting bodies can be mature harvest.
5 Harvest When the head of the monkey head has a diameter of 5 to 10 cm or nine mature, it can be harvested. When harvested, a small knife is used to cut the mushroom stalk, leaving 1 to 2 cm for regeneration. After harvesting, we will continue to strengthen the management of moisture, temperature and humidity. After about 10 days, we will grow new fruiting bodies. Generally, three tides can be collected per bag, and the bioconversion rate is 60% to 80%.
Hericium bag cultivation technology
Hericium, also known as hericium, fungus. It is a well-known food and drug-using bacterium in China. Hericium is a mesophilic temperature-varying fungus. The optimum growth temperature range for mycelia is 22～24°C, and the fruit body growth phase is 18～20°C. During the cultivation of bag materials, the mycelium growth stage has strict requirements on the air humidity, and the fruit body growth stage requires air humidity of 85%-90%. As long as the above temperature and humidity conditions are satisfied, the annual production can be organized.