98% Purity Recombinant Myostatin Gdf 8 Human Myostatin Propeptide (HMP)

98% Purity Recombinant Myostatin Gdf 8 Human Myostatin Propeptide (HMP)

Quick Details
GDF-8
Basic Info.
Alias: MSTN, Myostatin HMP
Purity: >98%
Specification: 1mg
Package: 10 Vials/Kit
Deliver:1 working day for ready goods 3~7 working days to your destination.




Myostatin (GDF-8) Introduction

Myostatin (GDF-8) is a member of the transforming grow factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength. The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.



GDF 8 / Myostatin Structure and mechanism of action

Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues. Its total molecular weight is 25.0 kDa. The protein is inactive until a protease cleaves the NH2-terminal, or "pro-domain" portion of the molecule, resulting in the active COOH-terminal dimer.

Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, in part through the activation of protein synthesis. However, Akt is not responsible for all of the observed muscle hyperthrophic effects which are mediated by myostatin inhibition Thus myostatin acts in two ways: by inhibiting muscle differentiation, and by inhibiting Akt-induced protein synthesis.



Our Advantage

FAQ

1. WHAT services do you offer?
We can offer the Custom premixes, Semi-Finished products, raw steroid horm ** powder.We can also assist with formulations, blends and custom packing. We are your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.

2. HOW do I make an order?
Simply contact us by telephone or email.We will connect you with one of our managers who will be happy to assist you with your order.Rip Cut 175 Mg/Ml Homebrew Injectable Oil Rip Cut 175

3. WHEN will my order ship?
Products in stock usually ship within 24hours of your order being received and processed. If a product is not in stock, turnaround time varies but is generally about 1-3 weeks, depending on availability.

4. DO you sell small quantities to end users?
We accept any quantity for order, from grams to tons.

5. DO you Identity Test your Products?
Yes, we test the ID for all incoming raw materials before production of the extracts in the country of origin. Testing ID before any processing takes place helps us to deliver you the highest quality ingredients at the lowest possible prices







We are the manufacturer of all kinds of horm ** powders. We focus on providing customers with high quality products, competitive price, best service and timely delivery. Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference. Payment methods: Western Union, MoneyGram We will supply the receiver's information or the bank account information for payment use. Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received. Every item will be shipped out in 2-3 working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment. We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

98% Purity Recombinant Myostatin Gdf 8 Human Myostatin Propeptide (HMP)

Quick Details
GDF-8
Basic Info.
Alias: MSTN, Myostatin HMP
Purity: >98%
Specification: 1mg
Package: 10 Vials/Kit
Deliver:1 working day for ready goods 3~7 working days to your destination.




Myostatin (GDF-8) Introduction

Myostatin (GDF-8) is a member of the transforming grow factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength. The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.



GDF 8 / Myostatin Structure and mechanism of action

Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues. Its total molecular weight is 25.0 kDa. The protein is inactive until a protease cleaves the NH2-terminal, or "pro-domain" portion of the molecule, resulting in the active COOH-terminal dimer.

Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, in part through the activation of protein synthesis. However, Akt is not responsible for all of the observed muscle hyperthrophic effects which are mediated by myostatin inhibition Thus myostatin acts in two ways: by inhibiting muscle differentiation, and by inhibiting Akt-induced protein synthesis.



Our Advantage

FAQ

1. WHAT services do you offer?
We can offer the Custom premixes, Semi-Finished products, raw steroid horm ** powder.We can also assist with formulations, blends and custom packing. We are your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.

2. HOW do I make an order?
Simply contact us by telephone or email.We will connect you with one of our managers who will be happy to assist you with your order.Rip Cut 175 Mg/Ml Homebrew Injectable Oil Rip Cut 175

3. WHEN will my order ship?
Products in stock usually ship within 24hours of your order being received and processed. If a product is not in stock, turnaround time varies but is generally about 1-3 weeks, depending on availability.

4. DO you sell small quantities to end users?
We accept any quantity for order, from grams to tons.

5. DO you Identity Test your Products?
Yes, we test the ID for all incoming raw materials before production of the extracts in the country of origin. Testing ID before any processing takes place helps us to deliver you the highest quality ingredients at the lowest possible prices







We are the manufacturer of all kinds of horm ** powders. We focus on providing customers with high quality products, competitive price, best service and timely delivery. Price: Please let us know the quantity you required, because for small order and bulk purchase, the price will be difference. Payment methods: Western Union, MoneyGram We will supply the receiver's information or the bank account information for payment use. Shipping items: Shipping items will be delivered by international express like EMS, TNT, UPS, FedEx or DHL after receiving received. Every item will be shipped out in 2-3 working days after the payment is done. The product usually arrives in 1-4 days based on the different destination, and online track is provided. Please kindly supply the shipping address, contact and tel number for successful shipment. We are 100% confident of my shipment method, None of our previous packages has ever had any delivery issues.

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